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Scientific Article

2011

Variants and haplotypes in angiotensinogen gene are associated with plasmatic angiotensinogen level in Mexican population.

Balam-Ortiz E., Esquivel-Villarreal A., Alfaro-Ruiz L., Carrillo K., Elizalde A., Gil T., Urushihara M., Kobori H., Jimenez-Sanchez G. Variants and haplotypes in angiotensinogen gene are associated with plasmatic angiotensinogen level in Mexican population. Am J Med Sci. 2011 Sep;342(3):205-11.

The plasmatic angiotensinogen (AGT) level has been associated with essential hypertension. Linkage analysis has found a relationship between the AGT gene locus and hypertension in the Mexican-American population, but studies have failed to identify genetic variants associated with hypertension or plasma AGT levels. This study analyzes the relationship between polymorphisms in the AGT gene and plasmatic AGT levels in Mexican population.

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