The Genotyping and Expression Analysis Unit at the INMEGEN has the necessary infrastructure to conduct experiments with the latest generation of genomic and expression microarrays  using the Affymetrix and Illumina platform. 

Affymetrix Plataform is used in the most academic and government institutions engaged in genomic research worlwide and a large number of pharmaceutical, diagnostics and biotechnology companies use Affimetrix technology. At present, there are over 1,200 Affymetrix microarray systems globally, which have resulted in the publication of over 3,400 scientific papers in indexed journals.

The Unit has microarrays for genomic DNA analysis, with a capacity to analyze  10,000, 50,000, 100,000 to 500,000 SNPs simultaneously in individual samples. This capacity enables the conduction of population studies, as well as linkage or association studies between diseases and specific genomic variations, and studies on altered numbers of DNA copies, which are particularly relevant to the study of neoplastic conditions.

The versatility of this unit  includes the capacity to analize human, rate and mouse expression microarrays. This type of microarrays allow to carry out experiments that compare  bosses of gene expression in diverse experimental or pathological conditions, including changes caused by the exhibition to medicaments.

The automated platform of genotipificación and analysis of expression Illumina has the highest technology to realize experimental protocols of genomic in that rate and mouse are analyzed simultaneously from hundreds up to a million genetic variations (type SNP), as well as essays of expression in complete genome of human being. This technology allows to identify genes and molecular profiiling associated with the predisposition to common diseases, the progression of the same ones and the response to pharmacological treatments. The technological platform Illumina is innovative, flexible, automated, robust and scalable, allowing the design of microarrangements the measure of the needs of the user.

The Unit offers advising in the experimental design, reliable delivery of information in different formats, quantitative information and images, repetition of unsuccessful essays, rigorous quality controls, simultaneous processing of multiple samples, equipments of last generation, automated protocols, high capacity of calculation, specialized, qualified and updated personal, and direct advising and on line of the company Illumina with personal specialized in design of microarrays, experimental designs and bioinformatic.

The services the Unit offers inside the INMEGEN include Whole-Genome Genotiping Analisys (Microarrays from 300 thousand up to 1 million variations of one nucleotide (SNP's), Microarrays for multiple samples (2 and 4 samples), content of Variations in Number of Copy, SNP's's content in genome mitocondrial, etc.),  FIne Mapping Genotiping Analisys (commercial Microarrays, páneles specific, or design personalized to the measure of the researcher, Chips for the simultaneous processing of up to 96 samples, assistance in SNP's' selection, analysis up 1536 SNP's), Analysis of Gene expression (Processing of up to 8 samples for Chip, analysis up to 48 thousand transcribed ones for sample, high degree of redundancy, detection of transcribed in cells and / or woven, specifics  panels for disease and / or species, etc.), and Essays of metilación (Capacity of analysis up to  27 thousand islands CpG's, resolution of an alone island CpG, páneles of up to 807 genes for the diagnosis of cancer, capacity of detection up to of 147,456 sites of mehtilation, evaluation up to of 14 thousand genes, etc.)

The projects referred to Genotyping and Expression Analysis Unit Illumina correspond to population studies of bond and / or association among diseases and genomic specific variations. In addition, the bosses' analysis of expression of genes, particularly relevant in the study of the neoplastic diseases, among others.