Cursó la licenciatura de biología en la Facultad de Ciencias de la UNAM; obtuvo el grado de Maestría en Ciencias Genómicas en la UACM y el Doctorado en Ciencias Genómicas de la misma Universidad. Actualmente, es Investigadora en Ciencias Médicas D, adscrita al Laboratorio de Genómica de las Enfermedades Psiquiátricas y Neurodegenerativas del INMEGEN y en el Hospital Psiquiátrico Infantil "Dr. Juan N. Navarro". Es miembro del Sistema Nacional de Investigadoras e Investigadores (SNII) Nivel 3.

Desde 2009 colabora en la línea de investigación de genómica de las enfermedades psiquiátricas y neurodegenerativas, englobando proyectos dirigidos a la búsqueda de marcadores de diagnóstico en esquizofrenia, trastorno bipolar, trastornos de la conducta alimentaria, trastorno neurodegenerativo, adicciones, entre otros temas. Esta línea ha tenido contribuciones importantes, tales como la búsqueda de genes asociados a la etiología y tratamiento de las enfermedades psiquiátricas.

Ha publicado más de 150 artículos de investigación en revistas internacionales y nacionales y 6 capítulos de libros, contando con más de 1500 citas. Ha dirigido 38 proyectos de tesis, que incluyen 4 de maestría, 15 de especialidad, 7 de alta especialidad,11 de licenciatura y 3 de doctorado. Desde 2014 es profesora titular del curso de especialidad en psiquiatría infantil y de la adolescencia en el Hospital Psiquiátrico Infantil "Dr. Juan N. Navarro", desde 2017 del curso de medicina genómica del IPN y desde 2021 del curso de Alta Especialidad en Medicina Genómica y Salud Mental en el Inmegen.

Es tutora de los siguientes posgrados: Ciencias Biológicas de la UNAM, Ciencias Médicas y Odontológicas de la UNAM, Neurobiología de la UNAM y Ciencias Biomédicas de la UJAT.

Ha sido galardonada con varias distinciones; en 2006 recibió el premio CANIFARMA-VETERINARIA “Dr. Alfredo Téllez Girón Rode” en investigación básica, en 2023 recibió el premio Beltrán Baguena al mejor artículo publicado en la revista español de geriatría y gerontología del año 2022, también en 2023 recibió el premio de los Institutos Nacionales de Salud como mejor artículo del área clínica del Encuentro Nacional de Investigadores de Salud de 2022.

Artículos

• Garcia-de la Cruz DD, Juarez-Rojop IE, Tovilla-Zarate CA, Nicolini H, Genis-Mendoza AD. Circulating Cell-Free Mitochondrial DNA in Plasma of Individuals with Schizophrenia and Cognitive Deficit in Mexican Population. Neuropsychiatr Dis Treat. 2024; 20:1757-1765.

• Nolasco-Rosales GA, Martinez-Magana JJ, Juarez-Rojop IE, Rodriguez-Sanchez E, Ruiz-Ramos D, Villatoro-Velazquez JA, Bustos-Gamino M, Medina-Mora ME, Tovilla-Zarate CA, Cruz-Castillo JD, Nicolini H, Genis-Mendoza AD. Phenome-Wide Association Study of Latent Autoimmune Diabetes from a Southern Mexican Population Implicates rs7305229 with Plasmatic Anti-Glutamic Acid Decarboxylase Autoantibody (GADA) Levels. Int J Mol Sci. 2024 Sep 21; 25(18):.

• Hernandez-Diaz Y, Genis-Mendoza AD, Gonzalez-Castro TB, Fresan A, Tovilla-Zarate CA, Lopez-Narvaez ML, Juarez-Rojop IE, Nicolini H. Exploring Candidate Gene Studies and Alexithymia: A Systematic Review. Genes (Basel). 2024 Aug 4; 15(8):None.

• Garzon Rodriguez N, Briceno-Balcazar I, Nicolini H, Martinez-Magana JJ, Genis-Mendoza AD, Flores-Lazaro JC, Villatoro Velazquez JA, Bustos Gamino M, Medina-Mora ME, Quiroz-Padilla MF. Exploring the relationship between admixture and genetic susceptibility to attention deficit hyperactivity disorder in two Latin American cohorts. J Hum Genet. 2024 May 7; :None.

• Martinez-Magana JJ, Genis-Mendoza AD, Gallegos-Silva I, Lopez-Narvaez ML, Juarez-Rojop IE, Diaz-Zagoya JC, Tovilla-Zarate CA, Gonzalez-Castro TB, Nicolini H, Solis-Medina A. Differential Alterations of Expression of the Serotoninergic System Genes and Mood-Related Behavior by Consumption of Aspartame or Potassium Acesulfame in Rats. Nutrients. 2024 Feb 8; 16(4):None.

• Hernandez-Diaz Y, Tovilla-Zarate CA, Castillo-Avila RG, Juarez-Rojop IE, Genis-Mendoza AD, Lopez-Narvaez ML, Villar-Juarez GE, Gonzalez-Castro TB. Association between the HTR1A rs6295 gene polymorphism and suicidal behavior: an updated meta-analysis. Eur Arch Psychiatry Clin Neurosci. 2023 Oct 10; 45:.

• Juarez-Rojop IE, Fresan A, Genis-Mendoza AD, Cerino-Palomino C, Nolasco-Rosales GA, Gonzalez-Castro TB, Lopez-Narvaez ML, Olan F, Villar-Soto M, Tovilla-Zarate CA, Nicolini H. Prevalence of Poor Sleep Quality and Associated Factors in Individuals with Rheumatoid Arthritis: A Cross-Sectional Study. Medicina (Kaunas). 2023 Sep 8; 59(9):None.

• Garzon Rodriguez N, Briceno-Balcazar I, Diaz-Barrera LE, Nicolini H, Genis-Mendoza AD, Flores-Lazaro JC, Quiroz-Padilla MF. Moderating effects of impulsivity and morning cortisol on the genotype-phenotype relationship of attention deficit hyperactivity disorder in young adults. Stress Health. 2024 Apr; 40(2):e3308.

• Gonzalez-Castro TB, Juarez-Rojop IE, Tovilla-Zarate CA, Ovando-Ricardez JA, Hernandez-Diaz Y, Lopez-Narvaez ML, Genis-Mendoza AD, Rodriguez-Perez C. Gene-environment interaction between HPA-axis genes and trauma exposure in the suicide behavior: A systematic review. J Psychiatr Res. 2023 Aug; 164:162-170.

• Nuncio-Mora L, Lanzagorta N, Nicolini H, Sarmiento E, Ortiz G, Sosa F, Genis-Mendoza AD. The Role of the Microbiome in First Episode of Psychosis. Biomedicines. 2023 Jun 20; 11(6):None.

• Gonzalez-Castro TB, Genis-Mendoza AD, Lopez-Narvaez ML, Juarez-Rojop IE, Ramos-Mendez MA, Tovilla-Zarate CA, Nicolini H. Gene Expression Analysis in Postmortem Brains from Individuals Who Died by Suicide: A Systematic Review. Brain Sci. 2023 Jun 3; 13(6):None.

• Garcia-Dolores F, Tendilla-Beltran H, Flores F, Carbajal-Rimoldi LA, Mendoza-Morales RC, Gomez-Mendoza LE, Vazquez-Hernandez AJ, de la Cruz F, Genis-Mendoza AD, Nicolini H, Flores G. Increased suicide rates in Mexico City during the COVID-19 pandemic outbreak: An analysis spanning from 2016 to 2021. Heliyon. 2023 Jun; 9(6):e16420.

• Nolasco-Rosales GA, Villar-Juarez GE, Perez-Osorio DA, Cruz-Castillo JD, Molina-Guzman G, Gonzalez-Castro TB, Tovilla-Zarate CA, Rodriguez-Sanchez E, Genis-Mendoza AD, Hernandez-Palacios F, Juarez-Rojop IE. Assessment of cognitive impairment and depressive signs in patients with type 2 diabetes treated with metformin from Southeast Mexico: A cross-sectional study. J Psychiatr Res. 2023 Jun; 162:65-70.

• Gutierrez-Rodriguez A, Cruz-Fuentes CS, Genis-Mendoza AD, Nicolini H. CRISPR/Cas9 Genome Editing Approaches for Psychiatric Research. Braz J Psychiatry. 2023 May 11; 45(2):137-145.

• Nolasco-Rosales GA, Ramirez-Gonzalez D, Rodriguez-Sanchez E, Avila-Fernandez A, Villar-Juarez GE, Gonzalez-Castro TB, Tovilla-Zarate CA, Guzman-Priego CG, Genis-Mendoza AD, Ble-Castillo JL, Marin-Medina A, Juarez-Rojop IE. Identification and phenotypic characterization of patients with LADA in a population of southeast Mexico. Sci Rep. 2023 Apr 29; 13(1):7029.

• Dionisio-Garcia DM, Genis-Mendoza AD, Gonzalez-Castro TB, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Hernandez-Diaz Y, Nicolini H, Olvera-Hernandez V. DNA Methylation of Genes Involved in the HPA Axis in Presence of Suicide Behavior: A Systematic Review. Brain Sci. 2023 Mar 30; 13(4):None.

• Cuevas Diaz P, Nicolini H, Nolasco-Rosales GA, Juarez Rojop I, Tovilla-Zarate CA, Rodriguez Sanchez E, Genis-Mendoza AD. Telomere Shortening in Three Diabetes Mellitus Types in a Mexican Sample. Biomedicines. 2023 Feb 28; 11(3):None.

• Garcia-Garcia ML, Tovilla-Zarate CA, Villar-Soto M, Juarez-Rojop IE, Gonzalez-Castro TB, Genis-Mendoza AD, Ramos-Mendez MA, Lopez-Narvaez ML, Saucedo-Osti AS, Ruiz-Quinones JA, Martinez-Magana JJ. Fluoxetine modulates the pro-inflammatory process of IL-6, IL-1beta and TNF-alpha levels in individuals with depression: a systematic review and meta-analysis. Psychiatry Res. 2022 Jan; 307:114317.

• Castillo-Avila RG, Genis-Mendoza AD, Juarez-Rojop IE, Lopez-Narvaez ML, Dionisio-Garcia DM, Nolasco-Rosales GA, Ramos-Mendez MA, Hernandez-Diaz Y, Tovilla-Zarate CA, Gonzalez-Castro TB, Nicolini H. High Serum Levels of IL-6 Are Associated with Suicide Attempt but Not with High Lethality Suicide Attempts: A Preliminary Case-Control Study. Int J Environ Res Public Health. 2022 NOV; 19(22):None.

• Genis-Mendoza AD, Gonzalez-Castro TB, Tovilla-Vidal G, Juarez-Rojop IE, Castillo-Avila RG, Lopez-Narvaez ML, Tovilla-Zarate CA, Sanchez-De la Cruz JP, Fresan A, Nicolini H. Increased Levels of HbA1c in Individuals with Type 2 Diabetes and Depression: A Meta-Analysis of 34 Studies with 68,398 Participants. Biomedicines. 2022 AUG; 10(8):None.

• Nicolini H, Sanchez-de la Cruz JP, Castillo Avila RG, Lopez-Narvaez ML, Gonzalez-Castro TB, Chavez-Manjarrez S, Montes-de-Oca JE, Martinez Magana J, Tovilla-Zarate CA, Genis Mendoza AD. Gender Differences in Suicide and Homicide Rates in Mexico City during 2019. Int J Environ Res Public Health. 2022 Jul 21; 19(14):.

• Genis-Mendoza AD, Hernandez-Diaz Y, Gonzalez-Castro TB, Tovilla-Zarate CA, Castillo-Avila RG, Lopez-Narvaez ML, Ramos-Mendez MA, Nicolini H. Association between TPH1 polymorphisms and the risk of suicide behavior: An updated meta-analysis of 18,398 individuals. Front Psychiatry. 2022 JUL 19; 13:None.

• Ramos-Mendez MA, Tovilla-Zarate CA, Juarez-Rojop IE, Villar-Soto M, Genis-Mendoza AD, Gonzalez-Castro TB, Lopez-Narvaez ML, Martinez-Magana JJ, Castillo-Avila RG, Villar-Juarez GE. Effect of risperidone on serum IL-6 levels in individuals with schizophrenia: a systematic review and meta-analysis. Int J Psychiatry Clin Pract. 2022 Jul 15; :1-8.

• Fresan A, Dionisio-Garcia DM, Gonzalez-Castro TB, Ramos-Mendez MA, Castillo-Avila RG, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Genis-Mendoza AD, Nicolini H. Cannabis smoking increases the risk of suicide ideation and suicide attempt in young individuals of 11-21 years: A systematic review and meta-analysis. J Psychiatr Res. 2022 Jul 1; 153:90-98.

• Genis-Mendoza AD, Dionisio-Garcia DM, Gonzalez-Castro TB, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Castillo-Avila RG, Nicolini H. Increased Levels of Cortisol in Individuals With Suicide Attempt and Its Relation With the Number of Suicide Attempts and Depression. Front Psychiatry. 2022; 13:912021.

• Hernandez-Diaz Y, Genis-Mendoza AD, Ramos-Mendez MA, Juarez-Rojop IE, Tovilla-Zarate CA, Gonzalez-Castro TB, Lopez-Narvaez ML, Nicolini H. Mental Health Impact of the COVID-19 Pandemic on Mexican Population: A Systematic Review. Int J Environ Res Public Health. 2022 Jun 6; 19(11):.

• Martinez-Magana JJ, Genis-Mendoza AD, Gonzalez-Covarrubias V, Juarez-Rojop IE, Tovilla-Zarate CA, Soberon X, Lanzagorta N, Nicolini H. Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis. Braz J Psychiatry. 2022 May 21; 1:.

• Perez-Aldana BE, Martinez-Magana JJ, Mayen-Lobo YG, Davila-Ortiz de Montellano DJ, Avina-Cervantes CL, Ortega-Vazquez A, Genis-Mendoza AD, Sarmiento E, Soto-Reyes E, Juarez-Rojop IE, Tovilla-Zarate CA, Gonzalez-Castro TB, Nicolini H, Lopez-Lopez M, Monroy-Jaramillo N. Clozapine Long-Term Treatment Might Reduce Epigenetic Age Through Hypomethylation of Longevity Regulatory Pathways Genes. Front Psychiatry. 2022; 13:870656.

• Genis-Mendoza AD, Fresan A, Gonzalez-Castro TB, Pool-Garcia S, Tovilla-Zarate CA, Castillo-Avila RG, Arias-Vazquez PI, Lopez-Narvaez ML, Nicolini H. Weak Hand Grip Strength Is Associated with Alexithymia in Outpatients in a Mexican Population. Brain Sci. 2022 Apr 29; 12(5):None.

• Martinez-Magana JJ, Hernandez S, Garcia AR, Cardoso-Barajas V, Sarmiento E, Camarena B, Caballero A, Gonzalez L, Villatoro-Velazquez JA, Medina-Mora ME, Bustos-Gamino M, Fleiz-Bautista C, Tovilla-Zarate CA, Juarez-Rojop IE, Nicolini H, Genis-Mendoza AD. Genome-Wide Analysis of Disordered Eating Behavior in the Mexican Population. Nutrients. 2022 Jan 17; 14(2):.

• Genis-Mendoza AD, Martinez-Magana JJ, Lopez-Narvaez ML, Gonzalez-Castro TB, Juarez-Rojop IE, Nicolini H, Tovilla-Zarate CA, Castillo-Avila RG. Mental Health Problems Due to Social Isolation During the COVID-19 Pandemic in a Mexican Population. Front Public Health. 2021; 9:703450.

• Martinez-Magana JJ, Genis-Mendoza AD, Santana D, Tovilla-Zarate CA, Lanzagorta N, Nicolini H. La presencia de algun trastorno psiquiatrico podria alterar el reloj epigenetico en gemelos monocigoticos. Rev Esp Geriatr Gerontol. 2021 Nov-Dec; 56(6):361-363.

• Gonzalez-Castro TB, Genis-Mendoza AD, Leon-Escalante DI, Hernandez-Diaz Y, Juarez-Rojop IE, Tovilla-Zarate CA, Lopez-Narvaez ML, Marin-Medina A, Nicolini H, Castillo-Avila RG, Ramos-Mendez MA. Possible Association of Cholesterol as a Biomarker in Suicide Behavior. Biomedicines. 2021 Oct 28; 9(11):None.

• Hernandez-Diaz Y, Genis-Mendoza AD, Gonzalez-Castro TB, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Nicolini H. Association and Genetic Expression between Genes Involved in HPA Axis and Suicide Behavior: A Systematic Review. Genes (Basel). 2021 Oct 13; 12(10):.

• Nolasco-Rosales GA, Martinez-Magana JJ, Juarez-Rojop IE, Gonzalez-Castro TB, Tovilla-Zarate CA, Garcia AR, Sarmiento E, Ruiz-Ramos D, Genis-Mendoza AD, Nicolini H. Association Study among Comethylation Modules, Genetic Polymorphisms and Clinical Features in Mexican Teenagers with Eating Disorders: Preliminary Results. Nutrients. 2021 Sep 15; 13(9):.

• Hernandez-Diaz Y, Gonzalez-Castro TB, Tovilla-Zarate CA, Lopez-Narvaez ML, Genis-Mendoza AD, Castillo-Avila RG, Ramos-Mendez MA, Juarez-Rojop IE. Oxytocin levels in individuals with schizophrenia are high in cerebrospinal fluid but low in serum: A systematic review and meta-analysis : Oxytocin and Schizophrenia. Metab Brain Dis. 2021 Sep 8; :.

• Fresan A, Genis-Mendoza AD, Lopez-Narvaez ML, Gomez-Peralta TG, Aguilar-Velazquez DG, Juarez-Rojop IE, Gonzalez-Castro TB, Tovilla-Zarate CA, Castillo-Avila RG, Nicolini H. Association between Short Hours of Sleep and Overweight/Obesity in Mexican Adolescent Population: A School-Based Cross-Sectional Study. Healthcare (Basel). 2021 Jul 26; 9(8):.

• Hernandez-Diaz Y, Gonzalez-Castro TB, Juarez-Rojop IE, Tovilla-Zarate CA, Lopez-Narvaez ML, Genis-Mendoza AD, Fresan A, Nicolini H. The role of rs242941, rs1876828, rs242939 and rs110402 polymorphisms of CRHR1 gene and the depression: systematic review and meta-analysis. Genes Genomics. 2021 Jul 19; :.

• Gonzalez-Castro TB, Tovilla-Zarate CA, Lopez-Narvaez ML, Genis-Mendoza AD, Juarez-Rojop IE. Interleukin-6 Levels in Serum, Plasma, and Cerebral Spinal Fluid in Individuals with Suicide Behavior: Systematic Review and Meta-Analysis with Meta-Regression. J Interferon Cytokine Res. 2021 Jul; 41(7):258-267.

• Hernandez-Diaz Y, Genis-Mendoza AD, Fresan A, Gonzalez-Castro TB, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Martinez-Magana JJ, Nicolini H. Knowledge, Emotions and Stressors in Front-Line Healthcare Workers during the COVID-19 Outbreak in Mexico. Int J Environ Res Public Health. 2021 May 25; 18(11):.

• Martinez-Damas MG, Genis-Mendoza AD, Perez-de la Cruz V, Canela-Tellez GD, Jimenez-Estrada I, Nicolini-Sanchez JH, Ramos-Chavez LA, Garcia S, Ramirez-Ramirez M, Coral-Vazquez RM. Epicatechin treatment generates resilience to chronic mild stress-induced depression in a murine model. Physiol Behav. 2021 Sep 1; 238:113466.

• Nicolini H, Martinez-Magana JJ, Genis-Mendoza AD, Villatoro Velazquez JA, Camarena B, Fleiz Bautista C, Bustos-Gamino M, Aguilar Garcia A, Lanzagorta N, Medina-Mora ME. Cannabis Use in People With Obsessive-Compulsive Symptomatology: Results From a Mexican Epidemiological Sample. Front Psychiatry. 2021; 12:664228.

• Ramos-Garcia M, Ble-Castillo JL, Garcia-Vazquez C, Tovilla-Zarate CA, Juarez-Rojop IE, Olvera-Hernandez V, Genis-Mendoza AD, Cordova-Uscanga R, Alvarez-Gonzalez CA, Diaz-Zagoya JC. Effects of Non-Nutritive Sweeteners on Energy Intake, Body Weight and Postprandial Glycemia in Healthy and with Altered Glycemic Response Rats. Foods. 2021 Apr 28; 10(5):.

• Rodriguez-Lopez ML, Martinez-Magana JJ, Ruiz-Ramos D, Garcia AR, Gonzalez L, Tovilla-Zarate CA, Sarmiento E, Juarez-Rojop IE, Nicolini H, Gonzalez-Castro TB, Genis-Mendoza AD. Individuals Diagnosed with Binge-Eating Disorder Have DNA Hypomethylated Sites in Genes of the Metabolic System: A Pilot Study. Nutrients. 2021 Apr 22; 13(5):.

• Ruiz-Ramos D, Martinez-Magana JJ, Garcia AR, Juarez-Rojop IE, Gonzalez-Castro TB, Tovilla-Zarate CA, Sarmiento E, Lopez-Narvaez ML, Nicolini H, Genis-Mendoza AD. Psychiatric Comorbidity in Mexican Adolescents with a Diagnosis of Eating Disorders Its Relationship with the Body Mass Index. Int J Environ Res Public Health. 2021 Apr 8; 18(8):.

• Martinez-Magana JJ, Genis-Mendoza AD, Villatoro Velazquez JA, Bustos-Gamino M, Juarez-Rojop IE, Tovilla-Zarate CA, Sarmiento E, Saucedo E, Rodriguez-Mayoral O, Fleiz-Bautista C, Camarena B, Aguilar A, Gonzalez-Castro TB, Medina-Mora ME, Nicolini H. Genome-wide association study of psychiatric and substance use comorbidity in Mexican individuals. Sci Rep. 2021 Mar 24; 11(1):6771.

• Bliskunova T, Genis-Mendoza AD, Martinez-Magana JJ, Vega-Sevey JG, Jimenez-Genchi J, Roche A, Guzman R, Zapata L, Castro-Chavira S, Fernandez T, Villatoro-Velazquez JA, Camarena B, Fleiz-Bautista C, Bustos-Gamino M, Medina-Mora ME, Nicolini H. Association of MGAT4C with major neurocognitive disorder in the Mexican population. Gene. 2021 Apr 30; 778:145484.

• Mayen-Lobo YG, Martinez-Magana JJ, Perez-Aldana BE, Ortega-Vazquez A, Genis-Mendoza AD, Davila-Ortiz de Montellano DJ, Soto-Reyes E, Nicolini H, Lopez-Lopez M, Monroy-Jaramillo N. Integrative Genomic-Epigenomic Analysis of Clozapine-Treated Patients with Refractory Psychosis. Pharmaceuticals (Basel). 2021 Feb 4; 14(2):.

• Cabrera-Mendoza B, Martinez-Magana JJ, Monroy-Jaramillo N, Genis-Mendoza AD, Fresno C, Fries GR, Walss-Bass C, Lopez Armenta M, Garcia-Dolores F, Diaz-Otanez CE, Flores G, Vazquez-Roque RA, Nicolini H. Candidate pharmacological treatments for substance use disorder and suicide identified by gene co-expression network-based drug repositioning. Am J Med Genet B Neuropsychiatr Genet. 2021 Jan 6; :.

• Genis-Mendoza AD, Elizalde-Martinez C, Martinez-Magana JJ, Cabrera-Mendoza B, Morales-Guadarrama A, Sacristan E, Beltran-Villalobos I, Tovilla-Zarate CA, Nicolini H. Longitudinal magnetic resonance evaluation of the schizophrenia model of neonatal lesion in the ventral hippocampus. Cir Cir. 2021; 89(6):785-791.

• Hernandez-Diaz Y, Gonzalez-Castro TB, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Perez-Hernandez N, Rodriguez-Perez JM, Genis-Mendoza AD. Association between polymorphisms of FKBP5 gene and suicide attempt in a Mexican population: A case-control study. Brain Res Bull. 2020 Jan; 166:37-43.

• Gonzalez-Castro TB, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Perez-Hernandez N, Rodriguez-Perez JM, Genis-Mendoza AD. The role of gene polymorphisms, and analysis of peripheral and central levels of interleukins in suicidal behavior: A systematic review. J Affect Disord. 2020 Jan 15; 279:398-411.

• Tovilla-Zárate, C.A., Robles-García R., Juárez-Rojop I.E., González-Castro T.B., López-Narváez M.L., Genis-Mendoza A.D., Mejía L.S., Fresán A.. From planning to action in smoking cessation: Demographic and psychological symptom dimensions related to readiness to quit smoking. Am J Med Genet. 2020 OCT; 19:None.

• Hernandez-Diaz Y, Gonzalez-Castro TB, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Perez-Hernandez N, Rodriguez-Perez JM, Genis-Mendoza AD, Nicolini H. The role of peripheral cortisol levels in suicide behavior: A systematic review and meta-analysis of 30 studies. Psychiatry Res. 2020 Nov; 293:113448.

• Genis Mendoza AD., Arroyo M., Morales Guadarrama A., Sacristán E., Nicolini H.. Lesion corroboration through MRI in the neonatal ventral hippocampal lesion rat model of schizophrenia. Am J Med Genet. 2020 SEP; 1(6):None.

• Genis-Mendoza AD, Martinez-Magana JJ, Ruiz-Ramos D, Gonzalez-Covarrubias V, Tovilla-Zarate CA, Narvaez MLL, Castro TBG, Juarez-Rojop IE, Nicolini H. Interaction of FTO rs9939609 and the native American-origin ABCA1 p.Arg230Cys with circulating leptin levels in Mexican adolescents diagnosed with eating disorders: Preliminary results. Psychiatry Res. 2020 Sep; 291:113270.

• Alma Delia Genis-Mendoza, Humberto Nicolini, Viana Manrique, Lilia Lopez-Canovas, Brenda Cabrera-Mendoza, Maria Antonieta Bobes, Nuria Lanzagorta, Daniel Santana. Association of antibody titers and 5-HTTLPR gene polymorphisms in pediatric autoimmune neuropsychiatric disorder associated with streptococci. Salud Ment. 2020 jul-aug ; 43(4):181-187.

• Castillo-Avila RG, González-Castro TB, Tovilla-Zárate CA, López-Narváez ML, Juárez-Rojop IE, Arias-Vázquez PI and Genis-Mendoza AD.. The Role of Rehabilitation in Individuals with Coronavirus COVID-19: A Comprehensive Review. Am J Med Genet. 2020 Jul-Aug; 1:None.

• Vega-Sevey JG, Martinez-Magana JJ, Genis-Mendoza AD, Escamilla M, Lanzagorta N, Tovilla-Zarate CA, Nicolini H. Copy number variants in siblings of Mexican origin concordant for schizophrenia or bipolar disorder. Psychiatry Res. 2020 May 17; 291:113018.

• Suarez-Mendez S, Garcia-de la Cruz DD, Tovilla-Zarate CA, Genis-Mendoza AD, Ramon-Torres RA, Gonzalez-Castro TB, Juarez-Rojop IE. Diverse roles of mtDNA in schizophrenia: Implications in its pathophysiology and as biomarker for cognitive impairment. Prog Biophys Mol Biol. 2020 Sep; 155:36-41.

• Cabrera-Mendoza B, Martinez-Magana JJ, Genis-Mendoza AD, Monroy-Jaramillo N, Walss-Bass C, Fries GR, Garcia-Dolores F, Lopez-Armenta M, Flores G, Vazquez-Roque RA, Nicolini H. Brain Gene Expression-DNA Methylation Correlation in Suicide Completers: Preliminary Results. Rev Invest Clin. 2020 May 7; 73(3):.

• Genis Mendoza AD., Martínez MagañaJJ., González Covarrubias V., Aguilar y Méndez D., Zapata Altamirano L., Santana Vargas D., Carrillo Ruiz JD., Nicolini H.. Exploratory analysis of auditory-evoked potentials and APOE-E4 as possible markers for cognitive impairment in elderly Mexican female patients. Am J Med Genet. 2020 MAY; 1(6):None.

• Martinez-Magana JJ, Genis-Mendoza AD, Villatoro Velazquez JA, Camarena B, Martin Del Campo Sanchez R, Fleiz Bautista C, Bustos Gamino M, Resendiz E, Aguilar A, Medina-Mora ME, Nicolini H. The Identification of Admixture Patterns Could Refine Pharmacogenetic Counseling: Analysis of a Population-Based Sample in Mexico. Front Pharmacol. 2020; 11:324.

• Gonzalez-Castro TB, Almeida de la O PLA, Tovilla-Zarate CA, Lopez-Narvaez ML, Genis Mendoza AD, Juarez-Rojop IE, Perez-Hernandez N, Rodriguez-Perez JM. Evaluation of leptin levels in serum as a biomarker for suicide behavior: systematic review and meta-analysis. Int J Neurosci. 2020 Feb 28; :1-7.

• Cabrera-Mendoza B, Fresno C, Monroy-Jaramillo N, Fries GR, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Mendoza-Morales RC, Garcia-Dolores F, Diaz-Otanez CE, Gonzalez-Saenz EE, Genis-Mendoza AD, Martinez-Magana JJ, Romero-Pimentel AL, Flores G, Vazquez-Roque RA, Nicolini H. Sex differences in brain gene expression among suicide completers. J Affect Disord. 2020 Apr 15; 267:67-77.

• Cabrera-Mendoza B, Martinez-Magana JJ, Genis-Mendoza AD, Sarmiento E, Ruiz-Ramos D, Tovilla-Zarate CA, Gonzalez-Castro TB, Juarez-Rojop IE, Garcia-de la Cruz DD, Lopez-Armenta M, Real F, Garcia-Dolores F, Flores G, Vazquez-Roque RA, Lanzagorta N, Escamilla M, Saucedo-Uribe E, Rodriguez-Mayoral O, Jimenez-Genchi J, Castaneda-Gonzalez C, Roche-Bergua A, Nicolini H. High polygenic burden is associated with blood DNA methylation changes in individuals with suicidal behavior. J Psychiatr Res. 2020 Apr; 123:62-71.

• Fajardo J., Albores-Gallo L., Genis-Mendoza AD., Martínez-Magaña JJ., Nicolini H.. Advanced paternal age as a risk factor for autism spectrum disorder in a Mexican population. Am J Med Genet. 2020 AGO; 43(3):None.

• Alma Delia Genis-Mendoza, José Jaime Martínez-Magaña, José Alberto Téllez-Martínez, Janet Jiménez-Guenchi, Andres Roche Carlos Castañeda, Carlos Alfonso Tovilla-Zarate, Humberto Nicolini. Identification of high impact variants in TREM2 and ABCA7 in Mexican individuals diagnosed with Alzheimer's disease. Am J Med Genet. 2020 ND; 1(8):None.

• Cabrera-Mendoza B, Fresno C, Monroy-Jaramillo N, Fries GR, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Genis-Mendoza AD, Martinez-Magana JJ, Romero-Pimentel AL, Diaz-Otanez CE, Garcia-Dolores F, Gonzalez-Saenz EE, Mendoza-Morales RC, Flores G, Vazquez-Roque R, Nicolini H. Brain Gene Expression Profiling of Individuals With Dual Diagnosis Who Died by Suicide. J Dual Diagn. 2020 Apr-Jun; 16(2):177-190.

• Cabrera B, Romero-Rebollar C, Jimenez-Angeles L, Genis-Mendoza AD, Flores J, Lanzagorta N, Arroyo M, de la Fuente-Sandoval C, Santana D, Medina-Banuelos V, Sacristan E, Nicolini H. Neuroanatomical features and its usefulness in classification of patients with PANDAS. CNS Spectr. 2019 Nov 15; 24:1-11.

• Gonzalez-Covarrubias V, Morales-Franco M, Cruz-Correa OF, Martinez-Hernandez A, Garcia-Ortiz H, Barajas-Olmos F, Genis-Mendoza AD, Martinez-Magana JJ, Nicolini H, Orozco L, Soberon X. Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico. Front Pharmacol. 2019; 10:1169.

• Gonzalez-Castro TB, Martinez-Magana JJ, Tovilla-Zarate CA, Juarez-Rojop IE, Sarmiento E, Genis-Mendoza AD, Nicolini H. Gene-level genome-wide association analysis of suicide attempt, a preliminary study in a psychiatric Mexican population. Mol Genet Genomic Med. 2019 Dec; 7(12):e983.

• Martinez-Magana JJ, Genis-Mendoza AD, Tovilla-Zarate CA, Gonzalez-Castro TB, Juarez-Rojop IE, Hernandez-Diaz Y, Martinez-Hernandez AG, Garcia-Ortiz H, Orozco L, Lopez-Narvaez ML, Nicolini H. Association between APOE polymorphisms and lipid profile in Mexican Amerindian population. Mol Genet Genomic Med. 2019 Nov; 7(11):e958.

• Gonzalez-Castro TB, Escobar-Chan YM, Fresan A, Lopez-Narvaez ML, Tovilla-Zarate CA, Juarez-Rojop IE, Ble-Castillo JL, Genis-Mendoza AD, Arias-Vazquez PI. Higher risk of depression in individuals with type 2 diabetes and obesity: Results of a meta-analysis. J Health Psychol. 2019 Sep 18; :1359105319876326.

• Rodriguez-Lopez ML, Martinez-Magana JJ, Cabrera-Mendoza B, Genis-Mendoza AD, Garcia-Dolores F, Lopez-Armenta M, Flores G, Vazquez-Roque RA, Nicolini H. Exploratory analysis of genetic variants influencing molecular traits in cerebral cortex of suicide completers. Am J Med Genet B Neuropsychiatr Genet. 2020 Jan; 183(1):26-37.

• Gomez-Pimienta E, Gonzalez-Castro TB, Fresan A, Juarez-Rojop IE, Martinez-Lopez MC, Barjau-Madrigal HA, Ramirez-Gonzalez IR, Martinez-Villasenor E, Rodriguez-Sanchez E, Villar-Soto M, Lopez-Narvaez ML, Tovilla-Zarate CA, Genis-Mendoza AD. Decreased Quality of Life in Individuals with Type 2 Diabetes Mellitus Is Associated with Emotional Distress. Int J Environ Res Public Health. 2019 Jul 25; 16(15):.

• Garcia-de la Cruz DD, Juarez-Rojop IE, Tovilla-Zarate CA, Martinez-Magana JJ, Genis-Mendoza AD, Nicolini H, Gonzalez-Castro TB, Guzman-Priego CG, Lopez-Martinez NA, Hernandez-Cisneros JA, Caballero-Prado F. Association between mitochondrial DNA and cognitive impairment in schizophrenia: study protocol for a Mexican population. Neuropsychiatr Dis Treat. 2019; 15:1717-1722.

• Genis-Mendoza AD, Ruiz-Ramos D, Lopez-Narvaez ML, Tovilla-Zarate CA, Rosa Garcia A, Cortes Meda G, Martinez-Magana JJ, Gonzalez-Castro TB, Juarez-Rojop IE, Nicolini H. Genetic association analysis of 5-HTR2A gene variants in eating disorders in a Mexican population. Brain Behav. 2019 Jul; 9(7):e01286.

• Gonzalez-Castro TB, Tovilla-Zarate CA, Genis-Mendoza AD, Juarez-Rojop IE, Nicolini H, Lopez-Narvaez ML, Martinez-Magana JJ. Identification of gene ontology and pathways implicated in suicide behavior: Systematic review and enrichment analysis of GWAS studies. Am J Med Genet B Neuropsychiatr Genet. 2019 May 2; 180:.

• Saucedo-Uribe E, Genis-Mendoza AD, Diaz-Anzaldua A, Martinez-Magana JJ, Tovilla-Zarate CA, Juarez-Rojop I, Lanzagorta N, Escamilla M, Gonzalez-Castro TB, Lopez Narvaez ML, Hernandez-Diaz Y, Nicolini H. Differential effects on neurodevelopment of FTO variants in obesity and bipolar disorder suggested by in silico prediction of functional impact: An analysis in Mexican population. Brain Behav. 2019 Apr 29; 9:e01249.

• Gonzalez-Castro TB, Genis-Mendoza AD, Tovilla-Zarate CA, Martinez-Magana JJ, Juarez-Rojop IE, Sarmiento E, Nicolini H. Genome-wide association study of suicide attempt in a Mexican population: a study protocol. BMJ Open. 2019 Apr 11; 9(4):e025335.

• Gonzalez-Castro TB, Genis-Mendoza AD, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Perez-Hernandez N, Rodriguez-Perez JM, Martinez-Magana JJ. Association between polymorphisms of NOS1, NOS2 and NOS3 genes and suicide behavior: a systematic review and meta-analysis. Metab Brain Dis. 2019 Aug; 34(4):967-977.

• Gonzalez-Castro TB, Pool-Garcia S, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Fresan A, Genis-Mendoza AD, Perez-Hernandez N, Nicolini H. Association between BDNF Val66Met polymorphism and generalized anxiety disorder and clinical characteristics in a Mexican population: A case-control study. Medicine (Baltimore). 2019 Mar; 98(11):e14838.

• Gonzalez-Castro TB, Juarez-Rojop IE, Lopez-Narvaez ML, Tovilla-Zarate CA, Genis-Mendoza AD, Perez-Hernandez N, Martinez-Magana JJ, Rodriguez-Perez JM. Genetic Polymorphisms of CCDC26 rs891835, rs6470745, and rs55705857 in Glioma Risk: A Systematic Review and Meta-analysis. Biochem Genet. 2019 Aug; 57(4):583-605.

• Martinez-Magana JJ, Genis-Mendoza AD, Gonzalez-Covarrubias V, Jimenez-Guenchi J, Galindo-Chavez AG, Roche-Bergua A, Castaneda-Gonzalez C, Lanzagorta N, Soberon X, Nicolini H. EXPLORATORY ANALYSIS OF RARE AND NOVEL VARIANTS IN MEXICAN PATIENTS DIAGNOSED WITH SCHIZOPHRENIA AND DEMENTIA. Rev Invest Clin. 2019; 71(4):246-254.

• Martinez-Magana JJ, Gonzalez-Castro TB, Genis-Mendoza AD, Tovilla-Zarate CA, Juarez-Rojop IE, Saucedo-Uribe E, Rodriguez-Mayoral O, Lanzagorta N, Escamilla M, Macias-Kauffer L, Nicolini H. EXPLORATORY ANALYSIS OF POLYGENIC RISK SCORES FOR PSYCHIATRIC DISORDERS: APPLIED TO DUAL DIAGNOSIS. Rev Invest Clin. 2019; 71(5):321-329.

• Solis-Medina A, Martinez-Magana JJ, Quintanar-Jurado V, Gallegos-Silva I, Juarez-Rojop IE, Tovilla-Zarate CA, Diaz-Zagoya JC, Hernandez-Diaz Y, Gonzalez-Castro TB, Lopez-Narvaez ML, Genis-Mendoza AD, Nicolini H. Astrogliosis and decreased neural viability as consequences of early consumption of aspartame and acesulfame potassium in male Wistar rats. Metab Brain Dis. 2018 Sep 28; :.

• Gonzalez-Castro TB, Hernandez-Diaz Y, Juarez-Rojop IE, Lopez-Narvaez ML, Tovilla-Zarate CA, Ramirez-Bello J, Perez-Hernandez N, Genis-Mendoza AD, Fresan A, Guzman-Priego CG. The role of COMT gene Val108/158Met polymorphism in suicidal behavior: systematic review and updated meta-analysis. Neuropsychiatr Dis Treat. 2018; 14:2485-2496.

• Martínez-Magaña JJ., Gonzalez-Castro TB., Genis-Mendoza AD., Tovilla-Zarate CA., Juarez-Rojop I., Saucedo-Uribe E., Lanzagorta N., Escamilla M., Macías-Kauffer L., Nicolini H.. An analysis on Dual Diagnosis Revealed a Possible deviation of Schizophrenia Polygenic Risk Score by Mexican Amerindian Ancestry. Am J Med Genet. 2018 2018; 1:None.

• Genis-Mendoza AD., Martínez-Magaña JJ., Bojórquez C., Téllez-Martínez JA., Jiménez-Genchi J., Roche A., Bojorge A., Chávez M., Castañeda C., Guzmán R., Zapata L., Aguilar-Méndez D., Lanzagorta N., Rebolledo I., Castro-Chavira S., Fernández T., Orozco L., Nicolini H., Martínez-Hernández AG.. Programa de detección del alelo APOE-E4 en adultos mayores mexicanos con deterioro cognitivo.. Gac Med Mex. 2018 2018; 154(5):None.

• Salas-Magaña M., Tovilla-Zárate CA., Genis A., González-Castro TB., Juárez-Rojop IE., López-Narvaez ML.. Polymorphism of the DRD2 Gene in a Mexican Population with Mental Deviations. Am J Med Genet. 2018 2018; 50(4):None.

• Genis-Mendoza AD, Tovilla-Zarate CA, Lopez-Narvaez L, Mendoza-Lorenzo P, Ostrosky-Wegman P, Nicolini H, Gonzalez-Castro TB, Hernandez-Diaz Y. Effect on the expression of drd2 and drd3 after neonatal lesion in the lymphocytes, nucleus accumbens, hippocampus and prefrontal cortex: comparative analysis between juvenile and adult Wistar rats. Hereditas. 2016; 153:13.

• Gonzalez-Castro TB, Hernandez-Diaz Y, Tovilla-Zarate CA, Gonzalez-Gutierrez KP, Fresan A, Juarez-Rojop IE, Lopez-Narvaez L, Villar Soto M, Genis A. Differences by gender in completed suicides in a Mexican population: A psychological autopsy study. J Forensic Leg Med. 2016 Feb; 38:70-4.

• Gonzalez-Castro TB, Tovilla-Zarate CA, Hernandez-Diaz Y, Fresan A, Juarez-Rojop IE, Ble-Castillo JL, Lopez-Narvaez L, Genis A, Hernandez-Alvarado MM. No association between ApoE and schizophrenia: Evidence of systematic review and updated meta-analysis. Schizophr Res. 2015 Dec; 169(1-3):355-368.

• Lopez-Narvaez ML, Tovilla-Zarate CA, Gonzalez-Castro TB, Juarez-Rojop I, Pool-Garcia S, Genis A, Ble-Castillo JL, Fresan A. Association analysis of TPH-1 and TPH-2 genes with suicidal behavior in patients with attempted suicide in Mexican population. Compr Psychiatry. 2015 Aug; 61:72-7.

• Garcia-Quinones JA, Sanchez-Dominguez CN, Serna-Rodriguez MF, Marino-Martinez IA, Rivas-Estilla AM, Perez-Maya AA, Nicolini H., Genis A.. Association between the SAT-1 Gene and Suicidal Behavior in Mexican Population. J Psychiatr Res. 2023 Feb 11; 1:.

• Genis-Mendoza AD, Beltran-Villalobos I, Nicolini-Sanchez H. Evaluacion conductual del fenotipo <> en un modelo animal por lesion neonatal del hipocampo ventral en ratas juveniles y adultas. Gac Med Mex. 2014 Sep-Oct; 150(5):420-31.

• Genis-Mendoza AD, Tovilla-Zarate CA, Nicolini H. Avances en genomica de los trastornos de la conducta alimentaria. Rev Colomb Psiquiatr. 2013 Dec; 42(4):350-5.

• Tovilla-Zarate C, Juarez-Rojop I, Peralta Jimenez Y, Jimenez MA, Vazquez S, Bermudez-Ocana D, Ramon-Frias T, Genis Mendoza AD, Garcia SP, Narvaez LL. Prevalence of anxiety and depression among outpatients with type 2 diabetes in the Mexican population. PLoS One. 2012; 7(5):e36887.

• Tovilla-Zarate C, Juarez-Rojop I, Ramon-Frias T, Villar-Soto M, Pool-Garcia S, Medellin BC, Genis Mendoza AD, Narvaez LL, Humberto N. No association between COMT val158met polymorphism and suicidal behavior: meta-analysis and new data. BMC Psychiatry. 2011 Sep 21; 11:151.

Tesista de Doctorado

• David Ruíz Ramos

Tesista de Maestría

• Lucero Nuncio Mora
• Paola Mejía Ortíz

Servicio Social

• Alaydee Samperio Villedas
• Ariadna Isabel Salazar García
• Fátima Portillo Rodríguez
• Fernanda Vera Casanova
• Olena Isabel Renee González Oldaster

Estancia Voluntaria

• Clara Villamil Castañeda
• Danae Camacho Rivero
• Elsa Ivette Ortega Mora
• Karla Paola Escamilla Tapia
• Kevin Oswaldo Hernández Vallejo

Estancia de verano

• Frida Monroy Basurto

En curso

• Análisis genómico y del microbioma intestinal como biomarcador auxiliar en el diagnóstico en pacientes con esquizofrenia del Hospital Psiquiátrico Fray Bernardino de Álvarez
• CARACTERIZACIÓN GENÓMICA-DIMENSIONAL DEL DESEMPEÑO DE LAS FUNCIONES EJECUTIVAS Y LA ATENCIÓN, EN ADULTOS JÓVENES CON TRASTORNO POR DEFICIT DE ATENCION
• Estudio del epigenoma en población con envejecimiento cognitivo exitoso en población latina
• GENÓMICA, METABOLÓMICA, Y MICROBIOMA DE LOS TRASTORNOS DE LA CONDUCTA ALIMENTARIA Y OBESIDAD
• Genómica y Adicciones. Subproyecto de la Encuesta Nacional de Consumo de Drogas, Alcohol y Tabaco, 2016

Terminados

• ANÁLISIS GENÓMICO-LONGITUDINAL DE INDIVIDUOS MEXICANOS CON ESTRÉS POSTRAUMÁTICO EN RESPUESTA A UN EVENTO SÍSIMICO DE MAGNITUD MAYO
• Estudio de asociación y longevidad del gen APOE en población indígena Mexicana
• Estudio del epigenoma en pacientes adolescentes y adultos con intento de suicidio y suicidio consumado
• Estudio del metaboloma en orina y plaquetas en enfermedades psiquiátricas
• Evaluación de la expresión de los genes de nicotina sobre la atención sostenida en el modelo animal de esquizofrenia por lesión neonatal del hipocampo ventral.
• Farmacogenómica de antipsicóticos en pacientes mexicanos
• Identificación de las variables genéticas comunes asociadas a enfermedades psiquiátricas en población mexicana mediante un microarreglo consensado para el diseño de un perfil de diagnóstico molecular
• Perfil inmunogenético en pacientes diagnosticados con espectro autista de origen mexicano
• Tamizaje del gen APOE y su asociación con demencia y psicosis en población de Mexicana
• Tamizaje inmunogenético en pacientes con Trastorno Bipolar