Sitio del Instituto Nacional de Medicina Genómica

Mariscal-Mendizabal LF, Sevilla-Montoya R, Martinez-Garcia AJ, Alaez-Verson C, Monroy-Munoz IE, Perez-Duran J, Ceron-Albarran JA, Carrillo-Sanchez K, Molina-Garay C, Flores-Lagunes LL, Jimenez-Olivares M, Aguinaga-Rios M. Clinical and genetic description of patients with prenatally identified cardiac tumors. Prenat Diagn. 2019 Jul 10; :.

Vazquez-Aguirre A, Gutierrez AG, Esparza RM, Hernandez-Lemus E, Ruiz-Azuara L, Mejia C. Autophagy Promotes Survival of CHP-212 Neuroblastoma Cells Treated With Casiopeinas(R). Anticancer Res. 2019 Jul; 39(7):3687-3695.

Ruderman A, Perez LO, Adhikari K, Navarro P, Ramallo V, Gallo C, Poletti G, Bedoya G, Bortolini MC, Acuna-Alonzo V, Canizales-Quinteros S, Rothhammer F, Ruiz-Linares A, Gonzalez-Jose R. Obesity, genomic ancestry, and socioeconomic variables in Latin American mestizos. Am J Hum Biol. 2019 Jun 24; :e23278.

Wojcik GL, Graff M, Nishimura KK, Tao R, Haessler J, Gignoux CR, Highland HM, Patel YM, Sorokin EP, Avery CL, Belbin GM, Bien SA, Cheng I, Cullina S, Hodonsky CJ, Hu Y, Huckins LM, Jeff J, Justice AE, Kocarnik JM, Lim U, Lin BM, Lu Y, Nelson SC, Park SL, Poisner H, Preuss MH, Richard MA, Schurmann C, Setiawan VW, Sockell A, Vahi K, Verbanck M, Vishnu A, Walker RW, Young KL, Zubair N, Acuna-Alonso V, Ambite JL, Barnes KC, Boerwinkle E, Bottinger EP, Bustamante CD, Caberto C, Canizales-Quinteros S, Conomos MP, Deelman E, Do R, Doheny K, Fernandez-Rhodes L, Fornage M, Hailu B, Heiss G, Henn BM, Hindorff LA, Jackson RD, Laurie CA, Laurie CC, Li Y, Lin DY, Moreno-Estrada A, Nadkarni G, Norman PJ, Pooler LC, Reiner AP, Romm J, Sabatti C, Sandoval K, Sheng X, Stahl EA, Stram DO, Thornton TA, Wassel CL, Wilkens LR, Winkler CA, Yoneyama S, Buyske S, Haiman CA, Kooperberg C, Le Marchand L, Loos RJF, Matise TC, North KE, Peters U, Kenny EE, Carlson CS. Genetic analyses of diverse populations improves discovery for complex traits. Nature. 2019 Jun; 570(7762):514-518.

Genis-Mendoza AD, Ruiz-Ramos D, Lopez-Narvaez ML, Tovilla-Zarate CA, Rosa Garcia A, Cortes Meda G, Martinez-Magana JJ, Gonzalez-Castro TB, Juarez-Rojop IE, Nicolini H. Genetic association analysis of 5-HTR2A gene variants in eating disorders in a Mexican population. Brain Behav. 2019 Jul; 9(7):e01286.

Madrazo-Moya CF, Cancino-Munoz I, Cuevas-Cordoba B, Gonzalez-Covarrubias V, Barbosa-Amezcua M, Soberon X, Muniz-Salazar R, Martinez-Guarneros A, Backer C, Zarrabal-Meza J, Sampieri-Ramirez C, Enciso-Moreno A, Lauzardo M, Comas I, Zenteno-Cuevas R. Whole genomic sequencing as a tool for diagnosis of drug and multidrug-resistance tuberculosis in an endemic region in Mexico. PLoS One. 2019; 14(6):e0213046.

Ramirez-Bello J, Jimenez-Morales S, Montufar-Robles I, Fragoso JM, Barbosa-Cobos RE, Saavedra MA, Sanchez-Munoz F. BLK and BANK1 polymorphisms and interactions are associated in Mexican patients with systemic lupus erythematosus. Inflamm Res. 2019 Aug; 68(8):705-713.

Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, Chen S, Contreras-Cubas C, Cordova E, Correa A, Cortes M, DeFronzo RA, Dolan L, Drews KL, Elliott A, Floyd JS, Gabriel S, Garay-Sevilla ME, Garcia-Ortiz H, Gross M, Han S, Heard-Costa NL, Jackson AU, Jorgensen ME, Kang HM, Kelsey M, Kim BJ, Koistinen HA, Kuusisto J, Leader JB, Linneberg A, Liu CT, Liu J, Lyssenko V, Manning AK, Marcketta A, Malacara-Hernandez JM, Martinez-Hernandez A, Matsuo K, Mayer-Davis E, Mendoza-Caamal E, Mohlke KL, Morrison AC, Ndungu A, Ng MCY, O'Dushlaine C, Payne AJ, Pihoker C, Post WS, Preuss M, Psaty BM, Vasan RS, Rayner NW, Reiner AP, Revilla-Monsalve C, Robertson NR, Santoro N, Schurmann C, So WY, Soberon X, Stringham HM, Strom TM, Tam CHT, Thameem F, Tomlinson B, Torres JM, Tracy RP, van Dam RM, Vujkovic M, Wang S, Welch RP, Witte DR, Wong TY, Atzmon G, Barzilai N, Blangero J, Bonnycastle LL, Bowden DW, Chambers JC, Chan E, Cheng CY, Cho YS, Collins FS, de Vries PS, Duggirala R, Glaser B, Gonzalez C, Gonzalez ME, Groop L, Kooner JS, Kwak SH, Laakso M, Lehman DM, Nilsson P, Spector TD, Tai ES, Tuomi T, Tuomilehto J, Wilson JG, Aguilar-Salinas CA, Bottinger E, Burke B, Carey DJ, Chan JCN, Dupuis J, Frossard P, Heckbert SR, Hwang MY, Kim YJ, Kirchner HL, Lee JY, Lee J, Loos RJF, Ma RCW, Morris AD, O'Donnell CJ, Palmer CNA, Pankow J, Park KS, Rasheed A, Saleheen D, Sim X, Small KS, Teo YY, Haiman C, Hanis CL, Henderson BE, Orozco L, Tusie-Luna T, Dewey FE, Baras A, Gieger C, Meitinger T, Strauch K, Lange L, Grarup N, Hansen T, Pedersen O, Zeitler P, Dabelea D, Abecasis G, Bell GI, Cox NJ, Seielstad M, Sladek R, Meigs JB, Rich SS, Rotter JI, Altshuler D, Burtt NP, Scott LJ, Morris AP, Florez JC, McCarthy MI, Boehnke M. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. 2019 Jun; 570(7759):71-76.

Martinez-Hernandez A, Larrosa J, Barajas-Olmos F, Garcia-Ortiz H, Mendoza-Caamal EC, Contreras-Cubas C, Mirzaeicheshmeh E, Lezana JL, Orozco L. Next-generation sequencing for identifying a novel/de novo pathogenic variant in a Mexican patient with cystic fibrosis: a case report. BMC Med Genomics. 2019 May 22; 12(1):68.

Salinas-Vera YM, Gallardo-Rincon D, Garcia-Vazquez R, Hernandez-de la Cruz ON, Marchat LA, Gonzalez-Barrios JA, Ruiz-Garcia E, Vazquez-Calzada C, Contreras-Sanzon E, Resendiz-Hernandez M, Astudillo-de la Vega H, Cruz-Colin JL, Campos-Parra AD, Lopez-Camarillo C. HypoxamiRs Profiling Identify miR-745 as a Regulator of the Early Stages of Vasculogenic Mimicry in SKOV3 Ovarian Cancer Cells. Front Oncol. 2019; 9:381.

Moran-Ramos S, Villarreal-Molina MT, Canizales-Quinteros S. Host Genetics, Diet, and Microbiome: The Role of AMY1. Trends Microbiol. 2019 May 2; :.

Gonzalez-Castro TB, Tovilla-Zarate CA, Genis-Mendoza AD, Juarez-Rojop IE, Nicolini H, Lopez-Narvaez ML, Martinez-Magana JJ. Identification of gene ontology and pathways implicated in suicide behavior: Systematic review and enrichment analysis of GWAS studies. Am J Med Genet B Neuropsychiatr Genet. 2019 May 2; :.

Garcia-de Teresa B, Frias S, Molina B, Villarreal MT, Rodriguez A, Carnevale A, Lopez-Hernandez G, Vollbrechtshausen L, Olaya-Vargas A, Torres L. FANCC Dutch founder mutation in a Mennonite family from Tamaulipas, Mexico. Mol Genet Genomic Med. 2019 May 1; :e710.

Lopez-Santibanez-Jacome L, Avendano-Vazquez SE, Flores-Jasso CF. The Pipeline Repertoire for Ig-Seq Analysis. Front Immunol. 2019; 10:899.

Saucedo-Uribe E, Genis-Mendoza AD, Diaz-Anzaldua A, Martinez-Magana JJ, Tovilla-Zarate CA, Juarez-Rojop I, Lanzagorta N, Escamilla M, Gonzalez-Castro TB, Lopez Narvaez ML, Hernandez-Diaz Y, Nicolini H. Differential effects on neurodevelopment of FTO variants in obesity and bipolar disorder suggested by in silico prediction of functional impact: An analysis in Mexican population. Brain Behav. 2019 Apr 29; :e01249.

Mendez-Garcia LA, Martinez-Castillo M, Villegas-Sepulveda N, Orozco L, Cordova EJ. Curcumin induces p53-independent inactivation of Nrf2 during oxidative stress-induced apoptosis. Hum Exp Toxicol. 2019 Aug; 38(8):951-961.

Reynolds AW, Mata-Miguez J, Miro-Herrans A, Briggs-Cloud M, Sylestine A, Barajas-Olmos F, Garcia-Ortiz H, Rzhetskaya M, Orozco L, Raff JA, Hayes MG, Bolnick DA. Comparing signals of natural selection between three Indigenous North American populations. Proc Natl Acad Sci USA. 2019 Apr 15; :.

Buxton MA, Meraz-Cruz N, Sanchez BN, Foxman B, Gronlund CJ, Beltran-Montoya J, Castillo-Castrejon M, O'Neill MS, Vadillo-Ortega F. Repeated Measures of Cervicovaginal Cytokines during Healthy Pregnancy: Understanding "Normal" Inflammation to Inform Future Screening. Am J Perinatol. 2019 Apr 12; :.

Marquez C, Nicolini H, Crowley MJ, Solis-Vivanco R. Early processing (N170) of infant faces in mothers of children with autism spectrum disorder and its association with maternal sensitivity. Autism Res. 2019 May; 12(5):744-758.

Gonzalez-Castro TB, Genis-Mendoza AD, Tovilla-Zarate CA, Martinez-Magana JJ, Juarez-Rojop IE, Sarmiento E, Nicolini H. Genome-wide association study of suicide attempt in a Mexican population: a study protocol. BMJ Open. 2019 Apr 11; 9(4):e025335.

Vallee Marcotte B, Guenard F, Marquis J, Charpagne A, Vadillo-Ortega F, Tejero ME, Binia A, Vohl MC. Genetic Risk Score Predictive of the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation in a Mexican Population. Nutrients. 2019 Mar 29; 11(4):.

Cornejo-Granados F, Calderon de la Barca AM, Torres N, Martinez-Romero E, Torres J, Lopez-Vidal Y, Soberon X, Partida-Martinez LP, Pinto-Cardoso S, Alcaraz LD, Pardo-Lopez L, Canizales-Quinteros S, Puente JL, Ochoa-Leyva A. Microbiome-MX 2018: microbiota and microbiome opportunities in Mexico, a megadiverse country. Res Microbiol. 2019 Jun - Aug; 170(4-5):235-241.

Gonzalez-Castro TB, Genis-Mendoza AD, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Perez-Hernandez N, Rodriguez-Perez JM, Martinez-Magana JJ. Association between polymorphisms of NOS1, NOS2 and NOS3 genes and suicide behavior: a systematic review and meta-analysis. Metab Brain Dis. 2019 Aug; 34(4):967-977.

Calvillo-Medina RP, Reyes-Grajeda JP, Moreno-Andrade VD, Barba-Escoto L, Bautista-de Lucio V, Jones GH, Campos-Guillen J. Bacterial Diversity Based on a 16S rRNA Gene Amplicon Data Set from a High-Altitude Crater Lake and Glacial Samples of the Iztaccihuatl Volcanic Complex (Mexico). Microbiol Resour Announc. 2019 Mar 21; 8(12):.

Barrientos-Rios R, Frias S, Velazquez-Aragon JA, Villaroel CE, Sanchez S, Molina B, Martinez A, Carnevale A, Garcia-de-Teresa B, Bonilla E, Alvarado-Araiza CD, Valderrama-Hernandez A, Rios-Gallardo PT, Calzada-Leon R, Altamirano-Bustamante N, Torres L. Low bone mineral density and renal malformation in Mexican patients with Turner syndrome are associated with single nucleotide variants in vitamin D-metabolism genes. Gynecol Endocrinol. 2019 Mar 19; :1-5.

Sanchez-Montes S, Colunga-Salas P, Fernandez-Figueroa EA, Medel MLH, Benitez CR, Becker I. Murine typhus in Mexico City: report of an imported case. Rev Inst Med Trop Sao Paulo. 2019 Mar 11; 61:e16.

Calvillo-Medina RP, Reyes-Grajeda JP, Barba-Escoto L, Hernandez-Bautista LA, Campos-Guillen J, Jones GH, Bautista-de Lucio VM. Proteome analysis of biofilm produced by a Fusarium falciforme keratitis infectious agent. Microb Pathog. 2019 Mar 6; :.

Gonzalez-Castro TB, Pool-Garcia S, Tovilla-Zarate CA, Juarez-Rojop IE, Lopez-Narvaez ML, Fresan A, Genis-Mendoza AD, Perez-Hernandez N, Nicolini H. Association between BDNF Val66Met polymorphism and generalized anxiety disorder and clinical characteristics in a Mexican population: A case-control study. Medicine (Baltimore). 2019 Mar; 98(11):e14838.

Ruiz-Zamora RA, Guillaume S, Al-Hilaly YK, Al-Garawi Z, Rodriguez-Alvarez FJ, Zavala-Padilla G, Perez-Carreon JI, Rodriguez-Ambriz SL, Herrera GA, Becerril-Lujan B, Ochoa-Leyva A, Melendez-Zajgla J, Serpell L, Del Pozo-Yauner L. The CDR1 and Other Regions of Immunoglobulin Light Chains are Hot Spots for Amyloid Aggregation. Sci Rep. 2019 Feb 28; 9(1):3123.

Lecoq L, Wiegand T, Rodriguez-Alvarez FJ, Cadalbert R, Herrera GA, Del Pozo-Yauner L, Meier BH, Bockmann A. A Substantial Structural Conversion of the Native Monomer Leads to in-Register Parallel Amyloid Fibril Formation in Light-Chain Amyloidosis. Chembiochem. 2019 Apr 15; 20(8):1027-1031.

Berumen J, Orozco L, Betancourt-Cravioto M, Gallardo H, Zulueta M, Mendizabal L, Simon L, Benuto RE, Ramirez-Campos E, Marin M, Juarez E, Garcia-Ortiz H, Martinez-Hernandez A, Venegas-Vega C, Peralta-Romero J, Cruz M, Tapia-Conyer R. Influence of obesity, parental history of diabetes, and genes in type 2 diabetes: A case-control study. Sci Rep. 2019 Feb 26; 9(1):2748.

Lira-Albarran S, Vega CC, Durand M, Rangel C, Larrea F. Functional genomic analysis of the human receptive endometrium transcriptome upon administration of mifepristone at the time of follicle rupture. Mol Cell Endocrinol. 2019 Apr 5; 485:88-96.

Gonzalez S, Villa E, Rodriguez M, Ramirez M, Zavala J, Armas R, Dassori A, Contreras J, Raventos H, Flores D, Jerez A, Ontiveros A, Nicolini H, Escamilla M. Fine-mapping scan of bipolar disorder susceptibility loci in Latino pedigrees. Am J Med Genet B Neuropsychiatr Genet. 2019 Feb 19; :.

Gonzalez-Castro TB, Juarez-Rojop IE, Lopez-Narvaez ML, Tovilla-Zarate CA, Genis-Mendoza AD, Perez-Hernandez N, Martinez-Magana JJ, Rodriguez-Perez JM. Genetic Polymorphisms of CCDC26 rs891835, rs6470745, and rs55705857 in Glioma Risk: A Systematic Review and Meta-analysis. Biochem Genet. 2019 Aug; 57(4):583-605.

Cervantes-Garduno A, Zampedri C, Espinosa M, Maldonado V, Melendez-Zajgla J, Ceballos-Cancino G. MT4-MMP Modulates the Expression of miRNAs in Breast Cancer Cells. Arch Med Res. 2019 Feb 18; :.

Cruz-Miranda GM, Hidalgo-Miranda A, Barcenas-Lopez DA, Nunez-Enriquez JC, Ramirez-Bello J, Mejia-Arangure JM, Jimenez-Morales S. Long Non-Coding RNA and Acute Leukemia. Int J Mol Sci. 2019 Feb 9; 20(3):.

Davila-Ortiz de Montellano DJ, Jara-Prado A, Rodriguez-Violante M, Camacho-Molina A, Carnevale A, Fresan-Orellana A, Camarena-Medellin B, Sanchez-Garcia D, Sotelo J. Low diagnostic accuracy of fragile X tremor/ataxia syndrome diagnostic criteria in late onset ataxia. Mov Disord. 2019 Feb 8; :.

Postolache TT, Del Bosque-Plata L, Jabbour S, Vergare M, Wu R, Gragnoli C. Co-shared genetics and possible risk gene pathway partially explain the comorbidity of schizophrenia, major depressive disorder, type 2 diabetes, and metabolic syndrome. Am J Med Genet B Neuropsychiatr Genet. 2019 Feb 6; :.

Borgonio-Cuadra VM, Valdez-Vargas C, Romero-Cordoba S, Hidalgo-Miranda A, Tapia-Guerrero Y, Cerecedo-Zapata CM, Hernandez-Hernandez O, Cisneros B, Magana JJ. Wide Profiling of Circulating MicroRNAs in Spinocerebellar Ataxia Type 7. Mol Neurobiol. 2019 Feb 5; :.

Cuevas-Cruz M, Lazcano-Perez F, Hernandez-Guzman U, Diaz de la Vega-Castaneda KH, Roman-Gonzalez SA, Valdez-Cruz NA, Velasco-Bejarano B, Colin-Gonzalez AL, Santamaria A, Gomez-Manzo S, Marcial-Quino J, Arreguin-Espinosa R. A Novel Phospholipase A2 Isolated from Palythoa caribaeorum Possesses Neurotoxic Activity. Toxins (Basel). 2019 Feb 1; 11(2):.

Castagnoli L, Cancila V, Cordoba-Romero SL, Faraci S, Talarico G, Belmonte B, Iorio MV, Milani M, Volpari T, Chiodoni C, Hidalgo-Miranda A, Tagliabue E, Tripodo C, Sangaletti S, Di Nicola M, Pupa SM. WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer. Oncogene. 2019 May; 38(21):4047-4060.

Velazquez-Caldelas TE, Alcala-Corona SA, Espinal-Enriquez J, Hernandez-Lemus E. Unveiling the Link Between Inflammation and Adaptive Immunity in Breast Cancer. Front Immunol. 2019; 10:56.

Adhikari K, Mendoza-Revilla J, Sohail A, Fuentes-Guajardo M, Lampert J, Chacon-Duque JC, Hurtado M, Villegas V, Granja V, Acuna-Alonzo V, Jaramillo C, Arias W, Lozano RB, Everardo P, Gomez-Valdes J, Villamil-Ramirez H, Silva de Cerqueira CC, Hunemeier T, Ramallo V, Schuler-Faccini L, Salzano FM, Gonzalez-Jose R, Bortolini MC, Canizales-Quinteros S, Gallo C, Poletti G, Bedoya G, Rothhammer F, Tobin DJ, Fumagalli M, Balding D, Ruiz-Linares A. A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Nat Commun. 2019 Jan 21; 10(1):358.

Beltran-Anaya FO, Romero-Cordoba S, Rebollar-Vega R, Arrieta O, Bautista-Pina V, Dominguez-Reyes C, Villegas-Carlos F, Tenorio-Torres A, Alfaro-Riuz L, Jimenez-Morales S, Cedro-Tanda A, Rios-Romero M, Reyes-Grajeda JP, Tagliabue E, Iorio MV, Hidalgo-Miranda A. Expression of long non-coding RNA ENSG00000226738 (LncKLHDC7B) is enriched in the immunomodulatory triple-negative breast cancer subtype and its alteration promotes cell migration, invasion, and resistance to cell death. Mol Oncol. 2019 Jan 16; :.

Martinez-Garcia M, Vallejo M, Hernandez-Lemus E, Alvarez-Diaz JA. Novel methods of qualitative analysis for health policy research. Health Res Policy Syst. 2019 Jan 14; 17(1):6.

Fernandez-Lopez JC, Romero-Cordoba S, Rebollar-Vega R, Alfaro-Ruiz LA, Jimenez-Morales S, Beltran-Anaya F, Arellano-Llamas R, Cedro-Tanda A, Rios-Romero M, Ramirez-Florencio M, Bautista-Pina V, Dominguez-Reyes C, Villegas-Carlos F, Tenorio-Torres A, Hidalgo-Miranda A. Population and breast cancer patients' analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population. Hum Genomics. 2019 Jan 10; 13(1):3.

Huerta-Chagoya A, Moreno-Macias H, Fernandez-Lopez JC, Ordonez-Sanchez ML, Rodriguez-Guillen R, Contreras A, Hidalgo-Miranda A, Alfaro-Ruiz LA, Salazar-Fernandez EP, Moreno-Estrada A, Aguilar-Salinas CA, Tusie-Luna T. A panel of 32 AIMs suitable for population stratification correction and global ancestry estimation in Mexican mestizos. BMC Genet. 2019 Jan 8; 20(1):5.

Orlova Z, Pruefer F, Castro-Oropeza R, Ordaz-Ramos A, Zampedri C, Maldonado V, Vazquez-Santillan K, Melendez-Zajgla J. IKKepsilon regulates the breast cancer stem cell phenotype. Biochim Biophys Acta Mol Cell Res. 2019 Apr; 1866(4):598-611.

Hidalgo-Bravo A, Parra-Torres AY, Casas-Avila L, Jimenez-Ortega RF, Ramirez-Salazar EG, Patino N, Rivera-Paredez B, Salmeron J, Valdes-Flores M, Velazquez-Cruz R. Association of RMND1/CCDC170-ESR1 single nucleotide polymorphisms with hip fracture and osteoporosis in postmenopausal women. Climacteric. 2019 Jan 2; :1-8.

Camacho-Moctezuma B, Quevedo-Castillo M, Melendez-Zajgla J, Aquino-Jarquin G, Martinez-Ruiz GU. YY1 negatively regulates the XAF1 gene expression in prostate cancer. Biochem Biophys Res Commun. 2019 Jan 15; 508(3):973-979.

Garcia-Cruz C, Merino-Jimenez C, Ceja V, Aragon J, Siqueiros-Marquez L, Reyes-Grajeda JP, Montanez C. The dystrophin isoform Dp71eDelta71 is involved in neurite outgrowth and neuronal differentiation of PC12 cells. J Proteomics. 2019 Jan 16; 191:80-87.

Arenas-Hernandez M, Gomez-Lopez N, Garcia-Flores V, Rangel-Escareno C, Alvarez-Salas LM, Martinez-Acuna N, Vazquez-Perez JA, Vega-Sanchez R. Choriodecidual leukocytes display a unique gene expression signature in spontaneous labor at term. Genes Immun. 2019 Jan; 20(1):56-68.